Evidence-based comparison

PRP vs Steroid Injection

Steroid injections reduce inflammation quickly but do not repair tissue. PRP uses your own concentrated platelets to stimulate biological healing, with a slower but longer-lasting effect. The right choice depends on the diagnosis, tissue quality and your goals.

At a glance

CriterionPRPSteroid injection
Primary mechanismGrowth-factor mediated tissue healingAnti-inflammatory suppression
Onset of relief4–8 weeks24–72 hours
Typical duration6–18 months, often durable6–12 weeks; variable
Best evidenceTennis elbow, patellar and Achilles tendinopathy, early knee OAFrozen shoulder, bursitis, acute synovitis
Tissue effectRegenerative, no atrophyCan weaken tendons if repeated
Return to sport2–6 weeks graduatedOften immediate
Cost (Oxford, private)HigherLower

When PRP is preferred

  • Chronic tendinopathy that has failed physiotherapy
  • Mild-to-moderate osteoarthritis where you want to delay surgery
  • Repeated steroid injections would risk tendon damage

When Steroid injection is preferred

  • Acute inflammatory flare needing rapid relief
  • Frozen shoulder, subacromial bursitis, trigger finger
  • Short-term symptom control before an event or procedure

Bottom line

PRP is regenerative and best for chronic tendon or early joint problems. Steroid is anti-inflammatory and best for short-term relief in inflammatory conditions. Ultrasound guidance is essential for both.

Frequently asked questions

Can I have both?

Yes — sequenced correctly. A steroid injection can settle an acute flare, and PRP can follow once inflammation has calmed to stimulate healing.

Is PRP better than steroid for tennis elbow?

Randomised trials show PRP produces superior 6- and 12-month outcomes in chronic lateral epicondylopathy, while steroid gives faster short-term relief.

Related treatments

Not sure which is right for you?

Book a consultation — we'll examine, scan and recommend an evidence-based plan on the day.