Arthrosamid® knee injections in Oxford
Arthrosamid® is a non-biodegradable polyacrylamide hydrogel injected once into the knee joint. It cushions the joint and integrates with the synovial lining, giving durable pain relief for knee osteoarthritis without steroids or animal-derived hyaluronic acid.
Why patients choose GB Clinic
- Single injection — no repeat course needed
- Clinical studies show benefit sustained at 2+ years post-injection
- Steroid-free — safe for patients with diabetes or steroid sensitivity
- Suitable across the arthritis spectrum, including severe knee OA awaiting surgery
- Delivered under live ultrasound guidance to ensure accurate joint placement
- May defer or avoid knee replacement in selected patients
What to expect
Consultation and ultrasound (with X-ray review where available) to grade the arthritis and confirm suitability.
A single 1 ml Arthrosamid® injection is placed into the knee joint under live ultrasound — takes under 10 minutes.
Rest the knee for 24–48 hours, then gradually return to normal activity. A short strengthening plan helps consolidate the benefit.
Conditions we treat
How the procedure is performed
- Step 1Assessment & ultrasound scan
Clinical assessment with grading of the arthritis and diagnostic ultrasound of the knee to confirm Arthrosamid® is appropriate.
- Step 2Skin preparation & anaesthetic
The skin over the knee is cleaned with antiseptic and a small volume of local anaesthetic is used to numb the injection site.
- Step 3Ultrasound-guided injection
A single 1 ml dose of Arthrosamid® hydrogel is injected into the joint under live ultrasound to confirm intra-articular placement.
- Step 4Post-injection review
You rest briefly in clinic, receive a written aftercare plan and are booked for a follow-up review at six weeks.
Recovery timeline
Typical recovery milestones — your clinician will personalise this to your condition, activity level and rehab goals.
Mild soreness or a feeling of fullness in the knee; limit high-impact activity.
Return to normal daily activity and gentle walking; avoid running and heavy squats.
Progressive pain relief as the hydrogel integrates; guided strengthening programme begins.
Peak benefit typically reached; effect maintained at 12 and 24 months in published trials.
Clinical evidence & guidance
Our protocols are informed by recognised clinical guidance and peer-reviewed literature, including:
- NICE NG226 — Osteoarthritis in over 16s: diagnosis and management (2022)National Institute for Health and Care Excellence
- Bliddal et al. — Polyacrylamide hydrogel injection for knee osteoarthritis: 2-year follow-upJournal of Experimental Orthopaedics, 2021
- ESSR guidelines on musculoskeletal ultrasound-guided interventionsEuropean Society of Musculoskeletal Radiology
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Book your appointment today
Arthrosamid® from £1,650 per knee including consultation, ultrasound-guided injection and follow-up review.
Ready to speak to a clinician?
Leave your details and our team will call you back the same working day to discuss your symptoms and arrange a suitable appointment.
Prefer to talk now? Call 01865 317483.
Frequently asked questions
How long does Arthrosamid® last?
Published trials show meaningful pain relief maintained at 12 and 24 months, with real-world data suggesting even longer duration for many patients.
How is Arthrosamid® different from hyaluronic acid?
Hyaluronic acid is broken down by the joint over months. Arthrosamid® is not biodegradable — it integrates with the synovial lining and stays in place, giving longer-lasting cushioning.
When will I feel benefit?
Most patients notice improvement between weeks 2 and 8 as inflammation settles and the hydrogel integrates. We review at 6 weeks.
Are there side effects?
Mild soreness or swelling for 24–72 hours is common. Serious side effects are rare. We discuss all risks in full before booking.
Why patients choose GB Clinic Oxford
Every consultation is led by a senior HCPC-registered musculoskeletal clinician with post-graduate training in diagnostic ultrasound and injection therapy. That matters because the difference between a routine injection and one that genuinely changes your pain is millimetres of accuracy, a correct diagnosis, and a rehabilitation plan tailored to your goals. We invest in high-resolution imaging, single-use sterile consumables and evidence-based protocols so that the care you receive here matches — and often exceeds — what you'd expect from a tertiary NHS or private hospital service.
Because we're an independent MSK specialist clinic — not a general physiotherapy chain — every appointment gives you unhurried time with a decision-maker. There is no fragmented pathway: your scan, diagnosis, injection and rehab plan all happen in a single visit, with a written summary sent to you (and, if you'd like, to your GP or consultant) the same day.
Safety, governance and standards
Our injection therapists work within nationally recognised prescribing frameworks (Patient Group Directions and independent prescribing), and every clinician holds current professional indemnity insurance. We follow infection-control standards set by the Royal College of Radiologists and the Faculty of Sport & Exercise Medicine. Adverse-event rates for image-guided steroid and hyaluronic acid injections in our clinic are consistent with, or below, published international benchmarks.
We are part of the wider GB Clinics group, which brings shared clinical governance, peer review and continuing professional development to every location. If your treatment isn't the right answer we'll say so — and we work closely with orthopaedic surgeons, pain consultants, rheumatologists and radiologists across Oxford, London and the Thames Valley when onward referral is the safer option.
Serving Oxford and the surrounding area
Patients travel to see us from across Oxford — Botley, Summertown, Headington, Cowley, Iffley, Marston, Jericho and central Oxford — and from further afield including Abingdon, Witney, Kidlington, Bicester, Didcot, Wallingford, Wantage, Wheatley, Thame, Woodstock, Chipping Norton, Banbury, Henley-on-Thames and Reading. Free on-site parking, evening appointments and Saturday clinics make it easy to fit an appointment around work or family commitments. If travel is difficult, home visits can be arranged for assessment, follow-up physiotherapy and selected injections across most of Oxfordshire.
Whether you're a runner with a stubborn Achilles problem, a keen gardener whose knee is stopping you enjoying the weekends, or someone who simply wants to walk the dog or lift a grandchild without pain, our aim is the same: an accurate diagnosis, a treatment that has the best chance of working for you, and a clear plan for getting back to the things that matter.
Getting here
Easy to reach — and easy to park
We're in Elms Parade, Botley, just a few minutes from Oxford city centre with excellent transport links.
Free parking
2 hours free, right outside
Park directly in front of the clinic in the Elms Parade car park — 2 hours free for patients, no app or ticket needed for short visits.
From Oxford Railway Station
Approx. 1.5 miles (8 min by taxi, 20 min walk). Head west on Botley Road, continue straight across the A34 flyover into Westway, then turn right into Elms Parade.
Nearest bus stop
Elms Parade (Stop B1) — directly outside the clinic. Served by routes 4, 4A, 4B and 4C from Oxford city centre (every 10–15 min).
By car
Junction 8/9 of the A34, exit toward Botley. Postcode OX2 9LG for sat-nav.